A decoction of the whole plant is used in the treatment of abdominal pain, abscesses, arthritis, overeating etc[147, 218]. pp. The plant is considered specific for treating rheumatism and all types of neurological diseases. In America, only Alatopaederia occurs, 1 species is endemic to Mexico, the other occurs throughout South America. Anticancer activity: The 50% ethanolic extract showed anticancer activity against human epidermoid carcinoma of nasopharynx in tissue culture. The LDso of a 50% ethanolic extract of leaves was 1200 mg/kg in mice. Vietnam: dây mơ lông, dây mơ tròn, mơ tam thể. The fracture is fibrous, the exterior brownish and the internal colour light brown, with a bitter taste. (1934). Among the less-studied plants, Paederia foetida has been used by various ethnic tribes as food and medicine. Medical uses of Paederia foetida are mainly for intestinal health and to aid in the control of bowel function such as, anti-diarrheal and anti-dysentry. Found in the Himalayas from Dehradun eastwards, up to an altitude of 1800 m. It is also found in Bihar, Orissa, Bengal and Assam. The plant is having a broad spectrum of use as in treatment of hepatic disorders, rheumatoid arthritis, Extracts of P. foetida show interesting activities in the field of anti-inflammation, which could be of interest for the development of future active substances to be used in the treatment of rheumatic complaints. & Deka, P.C., 1999. About 70% of these plantlets were successfully transferred to soil. As per the properties and functions of the herb it is used in healing the problems related to intestinal health (particularly anti-diarrheal and anti-dysentery) and as a support for male health. Paederia tomentosa Blume (1826), Paederia chinensis Hance (1878), Paederia scandens (Lour.) It has been introduced into North America (North Carolina, Texas, Louisiana), Hawaii, Christmas Islands, Mauritius and Reunion as an ornamental and escaped. 2 volumes. The fruits are used to prevent toothache. It did not, however, affect adrenal weight or ascorbic acid content significantly, thus ruling out a stimulation of the adrenal-pituitary axis. The antioxidant activity of fresh and dried plant extracts of Paederia foetida and Syzygium aqueum were studied using β-carotene bleaching and the 2,2’-azinobis(3-ethyl-benzothiazoline-6-sulfonic acid) (ABTS) radical cation assay. In India, the juice of the root is also prescribed in piles, inflammation of the spleen, and pain in the chest and liver. Cookies help us deliver our services. Skunkvine also known as Paederia Foetida, is a fast growing vine having 7 m long stems that twine into other plants for support (climbs into tree canopies or crawls on the ground). An excellent, if rather terse, guide to the traditional medicinal uses of the plants of the region The root is mixed with gin and used as a treatment for back pain[ 348 De, S., Ravishankar, B. In India, the leaves are often boiled in soup to lessen their smell. There is very limited evidence to … In China, P. foetida is also used for the treatment of paralysis, to increase fertility, to help digestion, and also for insect bites. In Peninsular Malaysia and Java they are applied to swellings and bruises in general. Asperuloside was also isolated from other Rubiaceae , including Asperula odorata L. and several Coprosma species. Revised reprint. Asperuloside, paederoside and scandoside have been isolated from the leaf and stem. 6.03 Puff (1991) Selected aspects of the reproductive biology of Paederia L. (Rubiaceae - Paederieae). Paederia foetida is a herb that has traditionally been used for a variety of purposes that seem to be centered around either intestinal health (particularly anti-diarrheal and anti-dysentry) and as an invigorator for male health. Bees and butterflies have been observed to visit the flowers. 2 (I-Z) pp. The wealth of India: a dictionary of Indian raw materials & industrial products. Opera Botanica Belgica 3: 167 -178. Medicinal plants of Vietnam, Cambodia and Laos. Fitoterapia 65(4): 357-362. In Java, the leaves are also consumed as a vegetable, when mixed with grated coconut and spices. Anti-inflammatory activity of Paederia foetida. Over the past decade, herbal and ayurvedic drugs have become a subject of world importance, with both medicinal and economical implications. Activity was also observed in chronic models of adjuvant and formaldehyde arthritis in rats. It significantly enhanced the humoral antibody synthesis and early hypersensitivity (4 h) reaction but slightly inhibited the development of 24 h reaction. It may help to eliminate poisons collected in the system. The genus Paederia L.: a multidisciplinary study. P. foetida is protrandrous and self-incompatible; stigmas remain receptive for a short period only. Cancer Letters 102(1-2): 223-226. Medicinal Uses. The presence of alkaloids (α- andβ-paederine, aerial parts) and an essential oil have also been recorded. The plant is grown in East Asia. Paederia foetida is known for the strong, sulphurous odour exuded when its leaves or stems are crushed or bruised. 1241-2444. Investigation of the anti-inflammatory effects of Paederia foetida. The leaves are rich in carotene and vitamin C. Antiinflammatory activity: A 50% ethanolic extract of P. foetida exhibited antiinflammatory activity traced to the water fraction, which demonstrated activity in various acute and chronic test models, such as carrageenan-, histamine- and dextran-induced oedema in rats. 1-1240, Vol. In Ayurveda, the plant is used for treatment of arthritis, disorders of heart and kidney and it also serves as a widely used pain relieving massage oil. In the carrageenan pleurisy test in rats, it reduced the pleural exudate volume and inhibited the migration of leucocytes into the inflammatory site. All Rights Reserved Powered By: Planet Ayurveda, Infusion: 12-24 ml Decoction: 56-112 ml Powder: 2-4 g. relieve distension due to flatulence and in herpes infections. The leaves can be mixed in omelettes as well for intestinal mucus. In Peninsular Malaysia, the juice of the leaves is considered astringent, and is given to children for diarrhoea. Micropropagation is also successful. Uses. The water-soluble fraction was found to be non-toxic up to 2 g/kg (PO and IP) in rats and mice and it exerted no significant effect on gross general behaviour. The root is also used as an emetic. It reduced the degradation changes in the articular cartilage induced by ananase and in vitro studies using ananase-treated chick embryonic bones showed that the plant (at a dose of 10 mg/ml of the medium) enhanced … This fraction produced a significant inhibition of granulation tissue formation in cotton-pellet implanted rats. 12(2). The fruits are compressed, ellipsoid, red or black in colour. Gandha means, smell and prasarini means spreading. Especially the disease-modifying component merits attention. P. foetida is found from North-East India to China and Japan, southwards to Thailand, Malaysia, Indonesia and the Philippines. 11 volumes. Vol. P. foetida is mainly propagated by seed. It remained unaltered in carrageenan-induced oedema in adrenalectomised rats but in the carrageenan-induced pleurisy test in rats, it reduced pleural exudate volume and inhibited migration of leucocytes to the inflammatory site. Individual flowers are short-lived, open early in the morning and fall off after 2 days; entire inflorescences, however, bear flowers for a long period of time. More recently, the anti-inflammatory activity of the butanol fraction of a methanol extract of the defatted leaves of P. foetida was tested. Embelin has been isolated from the aerial parts. It also exhibited marked activity against annanase-induced degenerative osteo-arthritis. P. foetida is used on a local scale only. Journal of Ethnopharmacology 43(1): 31-38. P. foetida is harvested from the wild whenever needed. In: Puff (ed.) Lots of information on the uses of the plants of SE Asia. It significantly enhanced humoral antibody synthesis and the early hypersensitivity reaction, but slightly inhibited development of the 24 hour reaction. Monoterpenes such as linalol constitute the major components in the oil. The stem yields a strong and silky fibre, but it is not commercially exploited. & Srivastava, T.N., 1994. Furthermore, the in vitro antitumour-promoting effect of a methanolic extract containing the iridoids was tested against the Epstein-Barr virus. For intestinal problems, fresh leaves are pounded, water added, and the … The term prasarini (prasar = spread) indicates not only the spreading habit of the plant but the reputation of the drug for relaxing and 'spreading' parts of the body contracted by paralysis. The activity was dose dependent and showed a remarkable increase when the extract was administered intra peritoneally. Hepatoprotective activity: The methanol extract showed moderate hepatoprotective activity. For intestinal problems, fresh leaves are pounded, water added, and the filtered infusion is drunk regularly till convalescence. (Rubiaceae), Journal of Ethnopharmacology, 105, 125–130. Triterpenoids and saponins Ursolic acid, epifriedelinol, friedelin. In older investigations, decoctions of the plant showed significant anti-inflammatory action against formaldehyde-induced arthritis in non-adrenalectomized albino rats. The leaves of P. foetida are widely used in Asia and South-East Asia for the treatment of intestinal complaints such as colic, cramps, flatulence, dysentery and also for rheumatism and gout. They are commonly used for the treatment of intestinal complaints such as abdominal pain, colic, cramps, flatulence and dysentery; and are also used for treating rheumatism and gout [147, 218, 310 ]. The leaves of this plant have been excessively used in parts of Eastern Asian to help relieve herpes infections. Leaves decussate, simple, broadly ovate, elliptical-oblong to linear, 2-21 cm × 0.7-9 cm, base cordate, rounded or sometimes hastate, apex acute to acuminate, glabrous to variably hairy, sometimes indumentum whitish to golden yellow-brown; petiole 0.5-6(-9) cm long; stipules interpetiolar, rounded or ovate to triangular, 1.5-5 mm × 2-3 mm, usually entire, glabrous or hairy. The plant is considered to have great restorative powers, and the leaves may thus be mixed with food, boiled and eaten. Multiple shoots were obtained from shoot tips (1-2 cm long) derived from field-grown plants of P. foetida in Murashige and Skoog (MS) medium supplemented with 1 mg benzyladenine (BAP)/l within 7 days of culture. The unpleasant smell of the crushed leaves may play a role in superstitious beliefs, as it is associated with healing powers. An extensive climber, leaves ovate to lanceolate, entire, about 5 cm long and 2.5 cm broad, membranous with long petioles. Singh, S., Ray, B.K., Mathew, S., Buragohain, P., Gogoi, J., Gogoi, S., Sharma, B.K. P. foetida has (sub)globose fruits and a very wide distribution in South-East Asia while P. cruddasiana Prain has laterally compressed-ovoid fruits, which are distinctly winged, and which occurs from northern India, Bangladesh, Nepal, Bhutan to south-western China and Thailand. The leaves of P. foetida are widely used in Asia and South-East Asia for the treatment of intestinal complaints such as colic, cramps, flatulence, dysentery and also for rheumatism and gout. The leaves, in the form of a poultice, are applied to the abdomen to . It also grows in montane vegetation up to 3000 m altitude, on steep, forested slopes, or on sandy or rocky sea coasts. The roots are used as an emetic and the juice extracted from the roots is given in cases of inflammation of the spleen and for pains in the chest and liver. Council of Scientific and Industrial Research, 1948-1976. Trichostrongylus and Haemonchus spp. a-Paederine and ?-paederine have been isolated. A dictionary of the economic products of the Malay Peninsula. The Paederia Foetidais known for treating ailments like colic, flatulence, gout, diarrhea, infertility, paralysis, rheumatism, abscesses, and dysentery. The hepatoprotective potential of a leaf methanol extract has been assessed against CCl4-induced liver damage in the rat model. ... Paederia foetida L. . The results suggest that the plant extract has analgesic and antidiarrhoeal activities, supporting its uses in traditional medicine. P. foetida, which grows mainly in China, Bangladesh, India and Mauritius, has been used in folk medicine for the treatment of inflammation, piles, and diarrhea, while P. scandens is used to treat aches, jaundice, dysentery and dyspepsia as a folk medicine in the southern region of China, Vietnam, India and Japan. It is a host for the root-knot nematode Meloidogyne sp. Burkill, I.H., 1966. 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Journal of Ethnopharmacology, 105, 125–130 plant shows tonic, astringent and antiphlogistic actions has... Have medicinal properties for treating stomach ache and gastric problems inhabiting this practice! `` P. foetida is widespread and medicinal uses of paederia foetida throughout South-East Asia, and also Puccinia! Results also demonstrate that the plant is for arthritis and joint pain, gout etc the juice of the extract! Mg/Kg in mice ayurvedic medicines which has been used by various ethnic as! Well explored Paederia species ( Rubiaceae ) for anti-tumor promoters without affecting serum aspartate transaminase activity without affecting serum transaminase... Water added, and it is regarded as a vegetable, when given at 2-day in... Migration of leucocytes into the inflammatory site – widely used pain relieving massage oil Marma Gulika– in! Leaf and stem contain sitosterol, stigmasterol and campesterol when its leaves or stems are crushed or.. 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