View abstract. Creatine supplementation and exercise performance: an update. Kern M, Podewils LJ Vukovich M Buono MJ. Huyzen RJ, Harder MP, Huet RC, et al. Watanabe, A., Kato, N., and Kato, T. Effects of creatine on mental fatigue and cerebral hemoglobin oxygenation. Vilella AL, Limsuwat C, Williams DR, Seifert CF. Eur.J Appl.Physiol 2001;84(4):321-328. Mol.Genet.Metab 2002;77(4):326-331. Effects of creatine supplementation on glucose tolerance and insulin sensitivity in sedentary healthy males undergoing aerobic training. Available at: https://www.mensfitnessmagazine.com.au/2013/09/creatine-in-the-dock/. View abstract. View abstract. Gordon A, Hultman E, Kaijser L, et al. Taking creatine with medications that can harm the kidneys might increase the chance of kidney damage. Available at: www.medscape.com/reuters/prof/ 2000/06/06.13/20000613publ004.html (Accessed 13 June 2000). Myburgh KH, Bold A, Bellinger B, and et al. View abstract. Mol Cell Endocrinol. This is simply not the case. Clin.Rehabil. Preen, D., Dawson, B., Goodman, C., Lawrence, S., Beilby, J., and Ching, S. Pre-exercise oral creatine ingestion does not improve prolonged intermittent sprint exercise in humans. View abstract. J Gerontol A Biol.Sci.Med Sci. View abstract. View abstract. Usually, consumers do not report any adverse effects, but body mass increases. Inhibition of muscle phosphocreatine resynthesis by caffeine after creatine loading. This article examines the necessity, benefits and side effects of the creatine loading phase. Research shows that taking creatine by mouth daily for 2 years does not improve muscle strength, coordination, or symptoms in people with Huntington disease. View abstract. Volek, J. S., Ratamess, N. A., Rubin, M. R., Gomez, A. L., French, D. N., McGuigan, M. M., Scheett, T. P., Sharman, M. J., Hakkinen, K., and Kraemer, W. J. Am J Physiol 1996;271:E821-6. Huso, M. E., Hampl, J. S., Johnston, C. S., and Swan, P. D. Creatine supplementation influences substrate utilization at rest. View abstract. 2018 Dec 13;4:41. doi: 10.1186/s40795-018-0250-y. View abstract. Am J Physiol Endocrinol.Metab 2005;288(2):E347-E352. J Int Soc Sports Nutr. Lancet 1998;351:724. Lillie JW, O'Keefe M, Valinski H, et al. Curr.Opin.Clin Nutr.Metab Care 2000;3(6):497-502. Arthritis Care Res (Hoboken) 2013;65(9):1449-59. Gastroenterology 1989;97:1033-42. View abstract. Effect of low dose, short-term creatine supplementation on muscle power output in elite youth soccer players. View abstract. Int J Sports Med. Galvan E, Walker Dk, Simbo SY, et al. You should not take more Amplified Creatine 189 than directed on the label to avoid gastrointestinal side effects 3 4 5. Learn about potential creatine side effects. B., de Coo, I. F., Huijmans, J. G., Jakobs, C., van der Knaap, M. S., Salomons, G. S., and Mancini, G. M. Long-term follow-up and treatment in nine boys with X-linked creatine transporter defect. Creatine supplementation during resistance training in older adults - a meta-analysis. View abstract. Risk of adverse outcomes in females taking oral creatine monohydrate: a systematic review and meta-analysis. 1997;53(4):343-348. Some research shows that taking creatine daily does not improve lung function. View abstract. Neurology 12-12-2000;55(11):1748-1751. VAN Cutsem J, Roelands B, Pluym B, et al. Does long-term creatine supplementation impair kidney function in resistance-trained individuals consuming a high-protein diet? Is there a rationale for the use of creatine either as nutritional supplementation or drug administration in humans participating in a sport? Schulze, A., Hess, T., Wevers, R., Mayatepek, E., Bachert, P., Marescau, B., Knopp, M. V., De Deyn, P. P., Bremer, H. J., and Rating, D. Creatine deficiency syndrome caused by guanidinoacetate methyltransferase deficiency: diagnostic tools for a new inborn error of metabolism. View abstract. View abstract. View abstract. © 2005 - 2019 WebMD LLC. Urbanski, R. L., Vincent, W. J., and Yaspelkis, B. Gastrointestinal disturbances and muscle cramps have been reported occasionally in healthy individuals, but the effects are anecdotal. All forms of manufactured creatine may have side effects, including water retention, increased kidney stress, mood changes and energy loss after you stop taking the supplement. Br.J Sports Med 2000;34(4):284-288. Item, C. B., Mercimek-Mahmutoglu, S., Battini, R., Edlinger-Horvat, C., Stromberger, C., Bodamer, O., Muhl, A., Vilaseca, M. A., Korall, H., and Stockler-Ipsiroglu, S. Characterization of seven novel mutations in seven patients with GAMT deficiency. Semin.Liver Dis. View abstract. Can J Appl Physiol 1997;22:454-67. Creatine supplementation and resistance training in vulnerable older women: a randomized double-blind placebo-controlled clinical trial. View abstract. View abstract. Ann Rheum Dis 1985;44:199-201. A., Rankin, J. W., and Toderico, B. Creatine supplementation affects muscle creatine during energy restriction. Pauses in breathing that may be followed by low heart rate and low oxygen levels in newborns. (abstract) Res Q Exerc Sport 1997;68:233-40. Resistance training exercise and creatine in patients with Charcot-Marie-Tooth disease. The influence of oral creatine supplementation on muscle phosphocreatine resynthesis following intense contraction in man. J Strength.Cond.Res 2004;18(2):311-315. Injury to the brain, spine, or nerves (neurological trauma). Kre-Celazine® as a viable treatment for juvenile rheumatoid arthritis/juvenile idiopathic arthritis - a pilot study. Harris, R. C., Nevill, M., Harris, D. B., Fallowfield, J. L., Bogdanis, G. C., and Wise, J. View abstract. Vorgerd M, Grehl T, Jager M, et al. Carducci, C., Birarelli, M., Leuzzi, V., Carducci, C., Battini, R., Cioni, G., and Antonozzi, I. Guanidinoacetate and creatine plus creatinine assessment in physiologic fluids: an effective diagnostic tool for the biochemical diagnosis of arginine:glycine amidinotransferase and guanidinoacetate methyltransferase deficiencies. Consensus statement for standard of care in spinal muscular atrophy. Early research on the use of creatine by mouth in people with muscular dystrophy is not clear. View abstract. Some evidence shows that muscle strength and fatigue seem to improve after taking creatine daily for 8-16 weeks. La fosfocreatina nell'infarto miocardico acuto: studio randomizzato multicentrico. J Sports Med Phys Fitness 2002;42(3):320-329. Neuroprotective effects of creatine in a transgenic animal model of amyotrophic lateral sclerosis. J.Strength.Cond.Res. View abstract. View abstract. Eur.J Appl.Physiol 2001;84(6):533-539. View abstract. Med Sci Sports Exerc 1999;31:1108-10. Amyotroph.Lateral.Scler.Other Motor Neuron Disord. Creatine and beta-hydroxy-beta-methylbutyrate (HMB) additively increase lean body mass and muscle strength during a weight-training program. Mazzini, L., Balzarini, C., Colombo, R., Mora, G., Pastore, I., De Ambrogio, R., and Caligari, M. Effects of creatine supplementation on exercise performance and muscular strength in amyotrophic lateral sclerosis: preliminary results. Nutrition 2001;17:558-66.. View abstract. A., Handy, D., Holbrook, M., Palmisano, J., Beal, R., Loscalzo, J., and Eberhardt, R. T. The effect of L-arginine and creatine on vascular function and homocysteine metabolism. View abstract. Ilas, J., Muhl, A., and Stockler-Ipsiroglu, S. Guanidinoacetate methyltransferase (GAMT) deficiency: non-invasive enzymatic diagnosis of a newly recognized inborn error of metabolism. Kuehl K, Goldberg L, and Elliot D. Renal insufficiency after creatine supplementation in a college football athlete. View abstract. View abstract. Your body may take some time to get used to creatine supplements. Preen, D., Dawson, B., Goodman, C., Beilby, J., and Ching, S. Creatine supplementation: a comparison of loading and maintenance protocols on creatine uptake by human skeletal muscle. Grazioli I, Melzi G, and Strumia E. Multicenter controlled study of creatine phosphate in the treatment of heart failure. Powers, M. E., Arnold, B. L., Weltman, A. L., Perrin, D. H., Mistry, D., Kahler, D. M., Kraemer, W., and Volek, J. Creatine Supplementation Increases Total Body Water Without Altering Fluid Distribution. Vandenberghe K, Van Hecke P, Van Leemputte M, et al. Muscle Nerve 2006;34(5):586-594. Effect of phosphocreatine in congestive heart failure. Lobo DM, Tritto AC, da Silva LR, et al. Verhoeven, N. M., Salomons, G. S., and Jakobs, C. Laboratory diagnosis of defects of creatine biosynthesis and transport. Int J Sport Nutr.Exerc.Metab 2000;10(4):452-463. Exp Gerontol 2014;53:7-15. Delecluse, C., Diels, R., and Goris, M. Effect of creatine supplementation on intermittent sprint running performance in highly trained athletes. Hass CJ, Collins MA, Juncos JL. Effects of 30 days of creatine ingestion in older men. View abstract. View abstract. Early research shows that taking 5 grams of creatine four times daily for 5 days followed by 5 grams daily for 16 weeks improves strength in women with fibromyalgia. There are few reports that creatine supplementation has protective effects in heart, muscle and neurological diseases. Taking creatine daily for one year might slow eye damage and vision loss. Myburgh, K H FACSM, Bold, A*, Bellinger, B*, Wilson, G*, and Noakes, T D FACSM. View abstract. 2-[carbamimidoyl(methyl)amino]acetic acid, Cr, Creatin, Creatina, Créatine, Créatine Anhydre, Creatine Anhydrous, Creatine Citrate, Créatine Citrate, Creatine Ethyl Ester, Créatine Ethyl Ester, Creatine Ethyl Ester HCl, Créatine Ethyl Ester HCl, Creatine Gluconate, Creatine Hydrochloride, Créatine Kré Alkaline, Creatine Malate, Créatine Malate, Creatine Monohydrate, Créatine Monohydrate, Créatine Monohydratée, Creatine Pyroglutamate, Créatine Pyroglutamate, Creatine Pyruvate, Créatine Pyruvate, Dicreatine Malate, Dicréatine Malate, Di-Creatine Malate, Éthyle Ester de Créatine, Glycine, Kreatin, Kre-Alkalyn Pyruvate, Malate de Tricréatine, N-(aminoiminométhyl)-N-Méthyl, N-(aminoiminomethyl)-N methyl glycine, N-amidinosarcosine, Phosphocreatine, Phosphocréatine, Tricreatine HCA, Tricréatine HCA, Tricreatine Malate, Tricréatine Malate. 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